Sandra Beatriz Castillo Castaneda

Helix Lab Fellow, Class of Spring 2025
Sandr Beatriz Castillo Casta

University

Technical University of Denmark (DTU)

Company

Novo Nordisk A/S

Project title

Investigation of sustainable water effluent reuse from purified water production

Project description

A typical process for the core production of an API … Insulin consists of three main stages: fermentation, recovery, and purification. The core production is typically supported by the utility process that delivers a wide range of raw materials to the core production, for example, purified water.
Purified water is used for product and solvents dilutions and for the cleaning-in-place processes. Potable water is the input to the purified water production system, where the water is being softened by ion exchange, reverse osmosis and electrodeionization
(EDI). These processes generate a water effluent that represents the 37% of the total water input to our Manufacturing 1 facility.
In the current state, the water effluent from the purified water production is first waste-water-treated on site then second, recycled to the Kalundborg Commune Water Supply Department (KCWSD). Extending the limits of the process is the re-use, sustainably, of the effluent, which should be investigated

What was your motivation for becoming a Helix Lab Fellow?

My dream has always been to work in a large-scale production environment. One of my main motivations for joining the Helix Lab was the opportunity to engage directly with the industry in Kalundborg, gaining hands-on experience, networking and learning from experts in the field.

What is the most exciting part of being a Helix Lab Fellow? 

Beyond the professional growth, the being a Fellow offers invaluable personal and social benefits. The connections and friendships formed throughout the process make the thesis journey more enjoyable. Being part of a talented and diverse group, where we continuously exchange knowledge and support each other, has strengthened my critical thinking skills. Additionally, the guidance and encouragement from the Helix Lab team create a supportive environment that boosts our confidence and helps us navigate challenges with multiple perspectives.

What perspectives do you see for your future after being a Helix Lab Fellow?

I believe that being a Helix Lab Fellow has already had a significant impact on my personal and professional development, and I am confident it will open many doors for my future career. I hope to stay in the Kalundborg area and contribute to one of the companies in the region.